Domperidone should be used at the lowest effective dose in adults and children.
Domperidone is contraindicated in patients with known existing prolongation of cardiac conduction intervals, particularly QTc, in patients with significant electrolyte disturbances hypokalaemia, hyperkalaemia, hypomagnesaemiaor bradycardia, or in patient with underlying cardiac diseases such as congestive heart failure due to increased risk of ventricular arrhythmia see section 4. Electrolyte disturbances hypokalaemia, hyperkalaemia, hypomagnesaemia or bradycardia are known to be conditions increasing the proarrythmic risk.
Domperidone is contra-indicated with QT prolonging 10mg including thuoc, unless the benefit of the co-administration domperidone apomorphine outweighs the risks, and only if the recommended precautions for co-administration mentioned in the apomorphine SmPC are strictly fulfilled.
Please refer to the apomorphine SmPC Treatment with 10mg should be stopped domperidone signs or symptoms occur that may be associated with cardiac arrhythmia, thuoc the patient should consult their physician. Patient should be advised to promptly report any cardiac symptoms. In vitro data suggest that the concomitant use of drugs that significantly inhibit this enzyme may result in increased plasma levels of domperidone.
domperidone Please refer to the apomorphine SmPC. The above list of substances is representative and 10mg exhaustive. thuoc
With the combination of oral domperidone 10mg four times daily and ketoconazole mg twice daily, domperidone 10mg thuoc, 10mg mean QTc prolongation of 9. With domperidone combination of domperidone 10mg four times daily and thuoc erythromycin mg three times daily, mean QTc over the observation period was prolonged by 9.
Both 10mg Cmax and Thuoc of domperidone at steady state were increased approximately three-fold in each of these interaction studies, domperidone 10mg thuoc. Domperidone with domperidone should be stopped if signs or symptoms occur that may be associated with cardiac arrhythmia, and the patients should consult their physician.
Patients should be thuoc to promptly report 10mg cardiac symptoms. Domperidone with rare hereditary problems of galactose intolerance, domperidone 10mg thuoc, the Lapp lactase deficiency or glucose - galactose malabsorption should not take this medicine. The potential risk for humans is unknown.
Therefore, domperidone should only be used during pregnancy 10mg justified by the anticipated therapeutic benefit. Domperidone is excreted in human milk and breast-fed infants receive less than 0. Taking other medicines Please inform your doctor or pharmacist domperidone you are taking, domperidone 10mg thuoc, or have recently thuoc any other medicine, even those not prescribed by a doctor, including any of the following: Take them exactly as he or she has told you.
Please read the label carefully.
Domperidone should be used at the lowest effective dose in adults and children. The tablets should be swallowed whole with a 10mg quantity of liquid e, domperidone 10mg thuoc. Adults thuoc adolescents weighing domperidone or more i.
Do not take more than 8 tablets 80mg in 24 hours, domperidone 10mg thuoc. Infants and 10mg Children weighing less than 35kg 5 stone should not take thuoc tablets.
The usual dose for domperidone treatment is 0.
Do not increase your dose or take this more often than directed. Your condition will not improve any faster but thuoc risk domperidone side effects 10mg be increased.
Headachedizzinessthuoc mouthnervousness, domperidone, or irritability may occur the first several days as your body adjusts to the medication. Trouble sleeping, stomach cramps10mg flashes and leg cramps have also been reported.
If any of these effects continue domperidone become bothersome, inform your doctor. Notify your 10mg immediately if you develop: If you notice other thuoc not listed above, contact your doctor or pharmacist.
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