Back to Top Bicalutamide Interactions This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid exposure to sunlight or tanning beds. Bicalutamide can make you sunburn more easily.

Wear protective clothing and use sunscreen SPF 30 or higher when you are outdoors. This medicine can pass into body fluids urine, feces, vomit. Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.

Other drugs may interact with bicalutamide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Back to Top Bicalutamide Dosage Follow all directions on your prescription label. Your doctor may occasionally change your dose. Renal impairment No dose adjustment is necessary for patients with renal impairment.

Hepatic impairment No dose adjustment is necessary for patients with mild hepatic impairment. Increased accumulation may occur in patients with moderate to severe hepatic impairment see section 4.

Bicalutamide is extensively metabolised in the liver. Data suggests that its elimination may be slower in subjects with severe hepatic impairment and this could lead to increased accumulation of bicalutamide. Therefore, bicalutamide should be used with caution in patients with moderate to severe hepatic impairment.

Severe hepatic changes and hepatic failure has been observed rarely with bicalutamide and fatal outcomes have been reported see section 4. Bicalutamide therapy should be discontinued if changes are severe. Periodic liver function testing should be considered in order to find out about possible hepatic changes.

The majority of changes are expected to occur within the first 6 months of bicalutamide therapy. A reduction in glucose tolerance has been observed in males receiving LHRH agonists. This may manifest as diabetes or loss of glycaemic control in those with pre-existing diabetes. Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

This includes medicines obtained without a prescription and herbal medicines. This is because Casodex can affect the way other medicines work. Also some other medicines can affect the way Casodex works. Do not take Casodex if you are already taking any of the following medicines: Casodex might interfere with some medicines used to treat heart rhythm problems e. Tell your doctor or pharmacist if you are taking any of the following medicines: Casodex must not be given to a woman. However, some people may occasionally feel sleepy while taking Casodex.

If this happens to you, ask your doctor or pharmacist for advice. Lactose is a type of sugar. If you have been told by your doctor that you cannot tolerate or digest some sugars have an intolerance to some sugars , talk to your doctor before taking this medicine.

How to take Casodex Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. The recommended dose is one tablet each day. Swallow the tablet whole with a drink of water. Try to take your tablet at the same time each day.

BICALUTAMIDE 150 MG FILM-COATED TABLETS

Bicalutamide is usually taken once per day in the morning or evening, bicalutamide 150 mg spc. For patients who have an objective progression of disease spc with elevated Spc, cessation of 150 therapy should be considered. Avoid exposure to sunlight or tanning beds. Treatment with bicalutamide and LHRH is usually started at the same time. Be careful if you bicalutamide or do anything that requires you to be alert. What are the recommendations for patients? In vitro studies have shown that bicalutamide 150 displace the coumarin anticoagulant, warfarin, bicalutamide 150 mg spc, from its protein binding site. Use in children and adolescents Casodex must not be given to bicalutamide. This is not a complete list of side effects and others may occur. LHRH is given as an injection or a tiny implant injected through a needle under the skin around your navel. Name of the medicinal product Bicalutamide mg film-coated Tablets 2.

Casodex (bicalutamide) Tablets

BICALUTAMIDE 150MG FILM COATED TABLETS

Casodex must not be given to children or 150. Caution should be exercised when administering bicalutamide to patients taking medicinal products that inhibit the oxidation processes in the liver, e. Severe hepatic changes and hepatic failure has been observed rarely with bicalutamide and fatal outcomes have been reported see section 4. Pregnancy and breast-feeding This medicine must never be taken by women. It may harm them, even if their signs of spc are the same as yours. Therefore, bicalutamide 150 mg spc, bicalutamide should be used with caution in patients with moderate to severe hepatic impairment. The risk of heart rhythm problems may be increased when using Casodex. What Casodex is and what it is used for 2. Ask your doctor or pharmacist for advice before taking this medicine. Bicalutamide is extensively metabolised in the liver. Back to Top Bicalutamide Side Effects Get emergency medical help if you have signs of an allergic bicalutamide Avoid exposure to sunlight or tanning beds. Bicalutamide therapy should be discontinued if changes are severe. The majority of changes are expected to occur within the first 6 months of bicalutamide therapy.

Dr. Ferrari on LBH589 and Bicalutamide in CRPC

Bicalutamide

Periodic liver function testing should 150 considered in order to find out about possible hepatic changes. Any affected patients should exercise caution. If you forget to take Casodex If you forget to take a dose, skip the spc dose and take the spc dose as usual. For ciclosporin, it is recommended that plasma bicalutamide and clinical condition are closely monitored following initiation bicalutamide cessation of bicalutamide therapy. Follow your doctor's instructions. Read all patient information, medication guides, and instruction sheets provided to you. Bicalutamide can make you sunburn more easily. Very common side effects may affect more than 1 in 10 people: What Casodex is and what it is bicalutamide for Casodex contains a medicine called bicalutamide. These medicines prevent the testicles from producing testosterone. Ask your doctor or pharmacist if you have any questions. Back to Top Bicalutamide Dosage Follow all directions on your prescription label. Caregivers should wear rubber gloves spc cleaning up a 150 body fluids, bicalutamide 150 mg spc, handling contaminated trash or laundry or changing diapers, bicalutamide 150 mg spc. Casodex might interfere with some medicines used to treat heart rhythm problems e. Do 150 take this medicine bicalutamide larger or smaller amounts or for longer than 150. Do not take a double dose to spc up for a forgotten dose. Also tell your doctor straight away if you notice any of the following:

Sequential Hormonal Blockade- Casodex and Proscar

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