In coronary patients, the specific treatment for coronary insufficiency should be continued. If angina pectoris reappears or worsens Xatral XL should be discontinued. Patients should be warned that the tablet should be swallowed whole. Any other mode of administration, such as crunching, crushing, chewing, grinding or pounding to powder should be prohibited. These actions may lead to inappropriate release and absorption of the drug and therefore possible early adverse reactions. The 'Intraoperative Floppy Iris Syndrome' IFIS, a variant of small pupil syndrome has been observed during cataract surgery in some patients on or previously treated with alphablockers.
Although the risk of this event with alfuzosin appears very low, ophthalmic surgeons should be informed in advance of cataract surgery of current or past use of alphablockers, as IFIS may lead to increased procedural complications. The ophthalmologists should be prepared for possible modifications to their surgical technique.
Alfuzosin 10 mg prolonged release tablets contain hydrogenated castor oil which may cause stomach upset and diarrhoea. Combinations to be taken into account: Repeated mg daily dosing of ketoconazole, for seven days resulted in a 2.
Cmax and AUC of alfuzosin 10 mg, when administered as a single dose under fed conditions, increased 2. The administration of general anaesthetics to patients receiving Xatral XL could cause profound hypotension. It is recommended that the tablets be withdrawn 24 hours before surgery. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with alfuzosin.
Give a list of all your medicines to any healthcare provider who treats you. Back to Top Alfuzosin Dosage Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended. Alfuzosin is usually taken once daily just after a meal.
Do not take alfuzosin on an empty stomach. Take the medicine at the same time each day. Do not crush, chew, or break an extended-release tablet. Alfuzosin lowers blood pressure and may cause dizziness or fainting, especially when you first start taking it.
You may feel very dizzy when you first wake up. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. As with all alpha1-receptor blockers, alfuzosin should be used with caution in patients with acute cardiac failure. Patients with congenital QTc prolongation, with a known history of acquired QTc prolongation or who are taking drugs known to increase the QTc interval should be evaluated before and during the administration of alfuzosin.
Prolonged erections and priapism have been reported with alpha-1 blockers including alfuzosin in post marketing experience. If priapism is not treated immediately, it could result in penile tissue damage and permanent loss of potency, therefore the patient should seek immediate medical assistance see section 4. Precautions Care should be taken when alfuzosin is administered to patients who have had a pronounced hypotensive response to another alpha 1-blocker. Treatment should be initiated gradually in patients with hypersensitivity to alphablockers.
Besavar XL 10mg Tablets should be administered carefully to patients being treated with anti-hypertensive medication or nitrates see section 4. Blood pressure should be monitored regularly, especially at the beginning of treatment. In coronary patients, the specific treatment for coronary insufficiency should be continued.
If angina pectoris reappears or worsens Besavar XL should be discontinued. Patients should be warned that the tablet should be swallowed whole. Any other mode of administration, such as crunching, crushing, chewing, grinding or pounding to powder should be prohibited.
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