There are, however, no adequate and well-controlled studies in pregnant women. Nursing Mothers It is not known whether 10mg drug is excreted in human milk, flexeril 10mg 283. Because cyclobenzaprine is closely related to the tricyclic antidepressants, some of which are known to be excreted in human milk, caution should be exercised when FLEXERIL is administered to a nursing woman.
The elderly may also be more at risk for CNS adverse events such as hallucinations and confusion, cardiac events resulting in falls or other sequelaedrug-drug and drug-disease interactions. For these reasons, in the 283, cyclobenzaprine should be used only if clearly needed, flexeril 10mg 283. Multiple drug ingestion including alcohol is common in deliberate cyclobenzaprine overdose. As management of overdose is complex and changing, it is recommended that the physician contact a poison control center for current information on treatment.
Signs and symptoms of toxicity may develop rapidly after cyclobenzaprine overdose; therefore, hospital monitoring cyanocobalamin injection price required as soon as possible. Manifestations The most common effects associated with cyclobenzaprine overdose are drowsiness and tachycardia. Less frequent manifestations include tremoragitation, coma, ataxiahypertensionslurred speech, confusion, dizziness, nausea, vomiting, and hallucinations.
Rare but potentially critical manifestations of overdose are cardiac arrest, chest pain, cardiac dysrhythmias, severe hypotensionseizures, and neuroleptic malignant syndrome. Changes in the electrocardiogramflexeril in QRS axis or width, are clinically significant indicators of cyclobenzaprine toxicity. Management General As management of overdose is complex and changing, it is recommended that the physician contact a poison control center for current information on treatment.
In order to protect against the rare but potentially critical manifestations described above, obtain an ECG and immediately initiate cardiac monitoring. Protect the patient's airwayestablish an intravenous line and initiate gastric decontamination. If signs of toxicity occur at any time during this period, extended monitoring is required. Monitoring of plasma drug levels should not guide management of the patient.
Dialysis is probably of no value because of low plasma concentrations of the drug. This should include large volume gastric 10mg followed by activated charcoal. If consciousness is impaired, the airway should be secured flexeril to lavage and emesis is contraindicated.
Serum alkalinization, to a pH of 7. Type 1A and 1C antiarrhythmics are generally contraindicated e. Seizures should be controlled with benzodiazepines or, if these are ineffective, other anticonvulsants e. Physostigmine is not recommended except to treat life-threatening symptoms risperidone sleeping disorders have been unresponsive to other therapies, and then only in close consultation with a poison control center.
Psychiatric Follow-Up Since overdosage is often deliberate, patients may attempt suicide by other means during the recovery phase, flexeril 10mg 283. Psychiatric referral may be appropriate. Pediatric 283 The principles of management of child and adult overdosages are similar.
flexeril It is strongly recommended that the physician contact the local poison control center for specific pediatric treatment. Concomitant use of monoamine oxidase MAO inhibitors or within 14 days after their discontinuation. Hyperpyretic crisis seizures, flexeril 10mg 283, and deaths have occurred in patients receiving cyclobenzaprine or structurally similar tricyclic antidepressants concomitantly with MAO inhibitor 10mg.
Acute recovery phase of myocardial infarctionand patients with arrhythmias, heart block or conduction disturbances, or congestive heart failure, flexeril 10mg 283. It 283 ineffective in muscle spasm flexeril to central nervous system disease. Cyclobenzaprine reduced or abolished skeletal muscle hyperactivity in several animal models. Animal studies indicate that cyclobenzaprine does not act flexeril the neuromuscular junction or flexeril on 283 muscle. Such studies show 10mg cyclobenzaprine acts primarily within the central nervous system at brain 283 as opposed to spinal cord levels, although its action on the latter may contribute to its overall skeletal muscle relaxant activity.
283 studies in animals showed a similarity between the effects of cyclobenzaprine 10mg the structurally related tricyclic 10mgincluding reserpine antagonism, norepinephrine potentiation, flexeril 10mg 283, potent peripheral and central anticholinergic effects, and sedation.
Cyclobenzaprine caused slight to moderate increase in heart rate in 283. Tell your doctor if you are using: Flexeril list is not complete and there may be other drugs 10mg can interact with cyclobenzaprine.
Tell your doctor about all your prescription and over-the-counter medications, flexeril 10mg 283, vitamins, minerals, herbal products, and drugs prescribed by other doctors, flexeril 10mg 283. Do not start a new medication without telling your doctor. Where can I get more information? Your pharmacist can provide more information about cyclobenzaprine. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use 283 medication only for the indication prescribed.
Every flexeril has been made to ensure that the information provided by Cerner Multum, 10mg.
Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, flexeril 10mg 283, unless specifically indicated otherwise.
Multum's flexeril information 283 not endorse drugs, diagnose patients or recommend therapy. 10mg absence of a warning for a given drug or drug combination in no way should 10mg construed to indicate that the drug or drug flexeril is safe, effective or appropriate for any given patient, flexeril 10mg 283.
Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, flexeril 10mg 283, drug interactions, allergic reactions, or adverse effects. If you 283 questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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