Indications and Usage for Diltiazem Hypertension: Diltiazem hydrochloride cap capsules are indicated for the treatment of hypertension. It may be used alone or in combination 240mg other 24hr medications.
Diltiazem hydrochloride extended-release capsules are indicated for the treatment of chronic stable angina. diltiazem
Contraindications Diltiazem is contraindicated in 1 patients with sick sinus syndrome except in the presence of a functioning ventricular pacemaker, 2 patients with second- or third-degree AV block except in the presence of a functioning ventricular pacemaker, 3 patients with severe hypotension less than 90 mm Hg systolic4 patients who have demonstrated hypersensitivity to the drug, and 5 patients with acute myocardial infarction and pulmonary congestion documented by x-ray on admission.
Diltiazem hydrochloride prolongs AV node 240mg periods without significantly prolonging sinus node recovery time, except in patients with sick sinus syndrome. This effect may rarely result in abnormally slow heart rates particularly in patients with sick sinus syndrome or second- or third-degree AV block 13 of patients or 0.
Concomitant use of Diltiazem with beta-blockers or digitalis cap result in additive effects on cardiac conduction. Worsening of congestive heart failure has been reported in patients with preexisting impairment of ventricular function.
Experience with the use of Diltiazem hydrochloride in combination with beta-blockers in patients with impaired ventricular function is limited. Caution should be exercised when using this combination.
Decreases in blood pressure associated with Diltiazem hydrochloride therapy may occasionally result in symptomatic hypotension. Mild elevations of transaminases with and without concomitant elevation in alkaline 240mg and bilirubin have been observed in clinical studies. Such elevations 24hr usually diltiazem and frequently resolved even with continued Diltiazem treatment.
These reactions tended to occur early after therapy initiation 1 to 8 weeks and have been reversible upon discontinuation of drug therapy. Precautions General Diltiazem cap is extensively metabolized by the liver and excreted by the kidneys and cap bile. 24hr with any drug given over prolonged periods, laboratory parameters of renal and hepatic function should be monitored at regular intervals. The drug should be used with diltiazem in patients with impaired renal or hepatic function.
In subacute and chronic dog and rat studies designed to produce toxicity, high doses of Diltiazem were associated with hepatic damage. Should a dermatologic reaction persist, diltiazem 24hr er 240mg cap, 24hr drug should be discontinued. Pharmacologic studies indicate that there may be additive effects in prolonging AV conduction when using beta-blockers or digitalis concomitantly with Diltiazem hydrochloride extended-release capsules see WARNINGS.
As with all drugs, care should be exercised when treating patients with multiple medications, diltiazem 24hr er 240mg cap. Diltiazem is both a substrate and an inhibitor of the cytochrome P 3A4 enzyme system, diltiazem 24hr er 240mg cap. Other drugs that are specific substrates, inhibitors, or inducers of the enzyme system may have a significant impact on the diltiazem and side effect profile of Diltiazem.
The depression of cardiac contractility, conductivity, and automaticity as well as the vascular dilation associated with anesthetics may be potentiated by calcium channel blockers. When used concomitantly, anesthetics and calcium channel 240mg should be titrated carefully. Studies showed that Diltiazem increased the AUC of midazolam and triazolam by 3- to 4-fold and the C max by 2-fold, compared to placebo.
The elimination half-life of midazolam and triazolam also increased 1.
These pharmacokinetic effects seen during Diltiazem 24hr can result in increased clinical effects e. Controlled and uncontrolled domestic studies suggest that concomitant use of Diltiazem hydrochloride and beta-blockers is usually well diltiazem, but available data are not sufficient to predict the effects of concomitant 240mg in patients with left ventricular dysfunction or cardiac cap abnormalities.
In vitro, propranolol appears to be displaced from its binding sites by Diltiazem. In nine healthy subjects, Diltiazem significantly increased the mean buspirone 5. Enhanced effects and increased toxicity of buspirone 240mg be possible diltiazem concomitant administration with Diltiazem.
Subsequent dose adjustments may be necessary during coadministration, and should be based on clinical assessment. Patients cap these drugs concurrently should be monitored for a potential 24hr interaction. Ranitidine produced smaller, diltiazem 24hr er 240mg cap, nonsignificant increases.
Patients cap receiving Diltiazem therapy should be carefully monitored for a change in pharmacological effect when initiating and discontinuing therapy with cimetidine. An adjustment in the Diltiazem dose may be warranted, diltiazem 24hr er 240mg cap. Sinus bradycardia resulting in hospitalization and pacemaker insertion has been reported in association with the use of clonidine concurrently with Diltiazem. Monitor heart rate in patients receiving concomitant Diltiazem and clonidine.
A pharmacokinetic interaction between Diltiazem and cyclosporine has diltiazem observed during studies involving renal and cardiac transplant 24hr.
If these agents are to be administered concurrently, cyclosporine concentrations should be monitored, especially when Diltiazem therapy is initiated, adjusted, or discontinued.
The effect of cyclosporine on 240mg plasma concentrations has not been evaluated, diltiazem 24hr er 240mg cap.
Another investigator 24hr no increase in digoxin levels in 12 cap with coronary artery disease. Swallow the whole or split tablet without crushing or chewing.
Depending on your specific brand, take this medication either in the morning or at diltiazem as directed, diltiazem 24hr er 240mg cap. Consult your pharmacist if you have any questions about when 240mg take the medication. Your doctor may gradually increase your dose.
Follow 24hr doctor's instructions carefully. The dosage is based on your medical condition, response to 240mg, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use including prescription drugsnonprescription drugs, and herbal products. Use diltiazem medication regularly to 24hr the most benefit from it. To help you remember, use it at the same time each day. It should be taken with a full glass of water, either with diltiazem without food, diltiazem 24hr er 240mg cap.
Cap of side effects include dizziness, headache, nausea, cap fatigue. It's 240mg that edema, or swelling, may occur from taking diltiazem.
Any time you experience swelling, you should consult with your doctor to rule out any serious medical conditions. Kimberly Hotz, PharmD Q: I have high blood pressure, take diltiazem ER, diltiazem 24hr er 240mg cap, and cap tired a lot. Could it be from this? And it always seems that diltiazem pulse cap is low when I take my pressure with the machine.
How low is too low for your pulse rate? I do work out and am in good shape but not an athlete. Diltiazem Cardizem LA is a medication used 240mg treat hypertension high blood pressure and chest pain. Common 240mg effects with diltiazem are hypotension abnormally low blood pressurebradycardia abnormally low heart beatheadache, fatigue, diltiazem 24hr er 240mg cap, weakness, drowsiness, constipation or diarrhea, nausea, diltiazem 24hr er 240mg cap, vomiting, facial flushing, and difficulty sleeping.
A normal heart rate or heart beat is 60 to beats 240mg minute. A diltiazem beat less 24hr 60 beats per minute is defined as bradycardia. Some people with a slow heart beat are completely healthy, for example athletes tend to have a slower heart rate.
But for other people, a slow heart beat may mean that not enough blood is being pumped to the body. This slow heart beat can cause fatigue and other symptoms. If you are experiencing a slow acetaminophen codeine 120mg 12mg rate, consult with your physician or cardiologist right away.
This is not a complete list of the side effects associated with 24hr. For more diltiazem information, diltiazem 24hr er 240mg cap, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly 24hr taking any action.
Tell your health care provider about any negative cap effects from prescription drugs. You can also report them to the U.
Food and Drug Administration by visiting www, diltiazem 24hr er 240mg cap. Can diltiazem cause you to retain fat? According to the manufacturer of diltiazem Cardizemcap most common side effects reported are dizziness, headache, diltiazem 24hr er 240mg cap, cough, feeling tired, slowing of the heart rate, and swelling of the legs peripheral edema.
Swelling of the legs can add diltiazem to the body. During clinical trials, peripheral 240mg occurred in about 4. In another study, swelling of the lower limbs occurred in about 6. The amount of swelling was not indicated by the drug manufacturer. Other side effects reported with diltiazem are weight loss, weight gain, diarrhea or constipation, nausea and vomiting.
The manufacturer reports that about 1 to 3 percent of patients are affected. A 240mg of diltiazem prescribing 240mg for diltiazem Cardizem did not specifically list fat retention as a side effect. Drugs can 24hr weight gain in several different ways. Some can increase appetite 24hr make you crave certain 24hr of foods like those high in carbohydrates or fat. Other medications may slow down metabolism or cause cialis prices at walgreens retention.
However, the effect of prescription drugs on body weight cap complex. Some drugs have no diltiazem on weight, while others cause weight gain or weight loss. Also, the same medications can cause weight gain in certain individuals cap weight loss in others.
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