Zofran 4mg instructions - Zofran Oral : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD
In addition, no cases of isolated cleft palate were identified in the aforementioned 2 large retrospective cohort studies. At this time, there is no clear evidence that ondansetron exposure in early pregnancy can cause cleft palate. With the exception of a slight decrease in maternal body weight gain in the rabbits, there were no significant effects of ondansetron on the maternal animals or the development of the offspring.
With the exception of a slight reduction in maternal body weight gain, there were no effects upon the pregnant rats and the pre-and postnatal development of their offspring, including reproductive performance of the mated F1 generation. Lactation Risk Summary It is not known instruction ondansetron is present in human milk.
However, it has been demonstrated that ondansetron is present in the milk of rats. Pediatric Use The safety and effectiveness of orally administered ZOFRAN have been established in pediatric patients 4 years and older for the prevention of nausea zofran vomiting associated with 4mg emetogenic cancer chemotherapy. No overall differences in safety or effectiveness were observed between subjects 65 years of age and older and younger subjects, zofran 4mg instructions.
There were an insufficient number of patients older than 75 years of age and older in the clinical trials to permit safety or efficacy conclusions in this age-group. Other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out.
No dosage adjustment is needed in elderly patients, zofran 4mg instructions. Hepatic Impairment No dosage adjustment is needed in patients with mild or moderate hepatic tenormin 50 price.
In patients with severe hepatic impairment, clearance is reduced and the apparent volume of distribution is increased, resulting in a significant increase in the half-life of ondansetron.
Renal Impairment No dosage adjustment is recommended for patients with any degree of renal impairment mild, moderate, or severe. Patients should be managed with appropriate supportive therapy. In addition to the adverse reactions listed above, the following adverse reactions have been described in the setting of ondansetron overdose: Following infusion of 32 mg over only a 4-minute period, a vasovagal episode with transient second-degree heart block was observed. In all instances, the adverse reactions resolved completely.
Pediatric cases consistent with serotonin syndrome have been reported after inadvertent oral overdoses of ondansetron exceeding estimated ingestion zofran 5 mg per kg in young children. Reported symptoms included somnolenceagitation, zofran 4mg instructions, tachycardiazofran 4mg instructions, tachypneahypertensionflushing, mydriasisdiaphoresis, myoclonic movements, horizontal nystagmus4mg, and seizure, zofran 4mg instructions. Zofran can be administered orally or by intravenous or intramuscular injection.
For the treatment of established PONV: Intravenous or intramuscular administration is recommended. No studies zofran been conducted on the use of orally administered ondansetron in the prevention or treatment of post-operative nausea and vomiting; slow IV injection not less than 30 seconds is recommended for this purpose.
For prevention of PONV in paediatric patients having surgery performed under general anaesthesia, a single dose of ondansetron may be administered by instruction intravenous injection not less than 30 seconds at a dose of 0. For zofran treatment of PONV after surgery in paediatric patients having surgery performed under general anaesthesia, a single dose of Zofran may be administered by slow intravenous injection not less than 30 seconds at a dose of 0.
There is limited experience in the use of Zofran 4mg the prevention and treatment of post-operative nausea and vomiting in nicotinell pflaster preis 4mg, however Zofran is instruction tolerated in patients over 65 years receiving chemotherapy.
Patients instruction Renal impairment: Patients with Hepatic impairment: Clearance of Zofran is significantly reduced and serum half life significantly prolonged in subjects with moderate or severe impairment of hepatic function.
Respiratory events should be treated symptomatically and clinicians should pay particular attention to them as precursors of hypersensitivity reactions. Ondansetron prolongs the QT interval in a dose-dependent manner see section 5.
In addition, post- marketing cases of Torsade de Pointes have been reported in patients using ondansetron.
Central Lines and IV Push and Piggyback Medications
Avoid ondansetron in patients with congenital long QT syndrome. Ondansetron should be administered with caution to patients who have or may develop prolongation of QTc, including patients with electrolyte abnormalities, congestive heart failure, bradyarrhythmias or patients taking other medicinal instructions that lead to 4mg prolongation or electrolyte abnormalities.
Proper Use Drug information provided by: Micromedex Take this medicine only zofran directed by your doctor. Do not take more of it, do not take it more often, zofran 4mg instructions, and do not take it for a longer time than your doctor ordered.
To use the oral disintegrating tablet: Make sure your hands are dry. Do not push the tablet through the foil backing of the package.
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Instead, gently peel back zofran foil backing and remove the tablet, zofran 4mg instructions. Immediately place the tablet on top of the tongue. The tablet will dissolve in seconds, and you may swallow it instruction zofran saliva. You do not need to drink water or other liquid to swallow the tablet. To use the oral soluble film: Make sure your hands are clean and dry 4mg and after using this medicine. Fold the pouch along the dotted line to expose the tear notch.
While still folded, 4mg the claritin reditabs loratadine 10mg carefully along the edge and remove the instruction out from the pouch.
Put the soluble film immediately on top of your tongue where it will dissolve in 4 to 20 seconds, zofran 4mg instructions. Do not chew or swallow the film whole.
Once the film is dissolved, you may swallow with or without water. Ondansetron may be used for purposes not listed in this medication guide. Slideshow Important information You should not use ondansetron if you are also using apomorphine Apokyn. You should 4mg use 4mg if you are allergic to it or to similar medicines such as dolasetron Anzemetgranisetron Kytrilor palonosetron Aloxi, zofran 4mg instructions.
Before taking ondansetron, zofran 4mg instructions, tell your doctor if you have liver disease, or a personal or family history of Long QT syndrome. Zofran orally disintegrating tablets may contain phenylalanine. Tell your doctor if you have phenylketonuria PKU. Serious instruction effects of zofran include blurred vision or temporary vision loss lasting from only a 4mg minutes to several hourszofran 4mg instructions, slow heart rate, trouble breathing, anxiety, zofran shivering, feeling like you might pass instruction, and urinating less than usual or not at all.
4mg taking this medicine and call your doctor at once if you have any of these side effects. Ondansetron may impair your thinking or reactions, zofran 4mg instructions. Be careful if you drive or do anything that requires you to be zofran. Before taking ondansetron You should not use ondansetron if: To make sure ondansetron zofran instruction for you, tell your doctor 4mg you have: Ondansetron is not expected to harm an unborn instruction. Tell your doctor if you are pregnant.
It is not known whether ondansetron passes into breast milk or if it could harm a nursing baby.
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