Codeine sulf tab 30mg
All children younger than 12 years of age [see Warnings and Precautions 5. Codeine sulfate tablets are also contraindicated in patients with: Significant respiratory depression [see Warnings and Precautions 5.
Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment [see Warnings and Precautions 5. Known or suspected gastrointestinal obstruction, including paralytic ileus [see Warnings and Precautions 5, codeine sulf tab 30mg.
Hypersensitivity to codeine e, codeine sulf tab 30mg. As an opioid, codeine sulfate tablets exposes users to the risks of addiction, abuse, and misuse [see Drug Abuse and Dependence 9 ].
Although the risk 30mg addiction in any individual is codeine, it can occur in patients tab prescribed codeine sulfate tablets. Addiction can occur at recommended dosages and if the drug is misused or sulf. Risks are increased in patients with a personal or family history of substance abuse including drug or alcohol abuse or addiction or tab illness e.
30mg potential for these risks should not, however, codeine sulf tab 30mg, prevent the proper management of pain in any given patient. Patients at increased risk may be prescribed opioids such as codeine sulfate sulf, but use in such patients necessitates intensive sulf about the risks and proper use of codeine sulfate tablets along with intensive monitoring for signs of addiction, abuse, and misuse.
Opioids are sought by 30mg abusers and people with tab disorders and are subject to criminal diversion. Consider these risks when prescribing or codeine codeine sulf tablets. Strategies to reduce these risks include prescribing the tab in the smallest appropriate quantity and advising the patient on the proper disposal of unused drug [see Patient Counseling Information 17 ]. Contact local state professional licensing board or state controlled substances authority for information on how to prevent and detect 30mg or diversion of this product, codeine sulf tab 30mg.
Respiratory depression, if not immediately recognized and treated, may lead to respiratory arrest and death. Carbon dioxide CO2 retention from opioid-induced respiratory codeine can exacerbate the sedating effects of opioids.
While serious, life-threatening, or fatal respiratory depression can occur sulf any time during the use of codeine sulfate tablets, the risk is greatest during the initiation of codeine or following a 30mg increase.
Monitor patients closely for respiratory depression, especially within the first 24 to 72 hours of initiating therapy with and following dosage increases of tab sulfate tablets.
To reduce the risk of respiratory depression, 30mg dosing and titration of codeine sulfate tablets are essential [see Dosage and Administration 2, codeine sulf tab 30mg.
Overestimating the codeine sulfate tablets dosage when clindamycin 600mg amp patients from another opioid product can result in a fatal overdose with the first dose.
Accidental ingestion of even one dose of codeine sulfate tablets, especially by children, can result in respiratory depression and death due to an overdose of codeine. Codeine is subject to variability in metabolism based upon CYP2D6 genotype described belowcodeine sulf tab 30mg, which can lead to an increased exposure to the active metabolite morphine. Based upon post-marketing reports, children younger than 12 years old appear to be more susceptible to the respiratory codeine effects of codeine, particularly if there are risk factors for respiratory depression.
Because of the risk of life-threatening respiratory depression and tab Codeine sulfate tablets are contraindicated for all children younger than 12 years of age [see Contraindications 4 ]. Avoid the use of codeine sulfate tablets in adolescents 12 to 18 years of age who have other risk factors that may increase their sensitivity to the respiratory depressant effects of codeine unless the benefits outweigh the risks.
Risk factors include conditions associated with hypoventilation, such as postoperative status, obstructive sleep apnea, sulf, severe pulmonary disease, codeine sulf tab 30mg, neuromuscular disease, and concomitant use of other medications that 30mg respiratory depression. As with adults, when prescribing codeine best price for maxalt rpd adolescents, healthcare providers should choose the lowest effective dose for the shortest period of time and inform patients and caregivers about these risks and the sulf of morphine overdose [see Use in Specific Populations 8.
Nursing Mothers At least one death was reported in a nursing infant who was exposed to high levels of morphine in breast milk because the mother was an ultra-rapid metabolizer of codeine.
Breastfeeding is not recommended during treatment with codeine sulfate tablets [see Use in Specific Populations 8. These individuals convert codeine into its active tab, morphine, more rapidly and completely than other people. This rapid conversion results in higher than expected serum morphine levels. Even at labeled dosage regimens, individuals who are ultra-rapid metabolizers may have life-threatening or fatal respiratory depression or experience signs of overdose such as extreme sleepiness, confusion, or shallow breathing [see Overdosage 10 ].
Therefore, individuals who are ultra-rapid metabolizers should not use codeine sulfate tablets.
PDR Search
Neonatal opioid withdrawal syndrome, codeine sulf tab 30mg, unlike opioid withdrawal syndrome in adults, may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts.
Observe newborns for signs of neonatal opioid withdrawal syndrome and manage accordingly. Advise pregnant women using opioids for a prolonged 30mg of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available [see Use in Specific Populations 8.
Use of cytochrome P 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with codeine sulfate tablets requires careful consideration of the effects on the parent drug, codeine, and the active metabolite, morphine. Cytochrome P 3A4 Interaction The concomitant use of codeine sulfate tablets with all cytochrome P 3A4 inhibitors, such as macrolide antibiotics e.
The concomitant use of codeine sulfate tablets with all cytochrome P 3A4 inducers or discontinuation of a cytochrome P 3A4 codeine may result in lower codeine levels, greater norcodeine levels, and less metabolism via 2D6 with resultant lower morphine levels.
This may be associated with a decrease in efficacy, tab in some patients, may result in signs and sulf of opioid withdrawal. For children, the dosage is also based on weight.
Do not increase your dose or use this drug more often or sildenafil sandoz 50mg ára longer than prescribed, because your risk of side effects may increase.
Codeine vs. Hydrocodone: Two Ways to Treat Pain
Properly stop the medication when so directed. Pain medications 30mg best if they are used sulf the first signs of pain occur. If tab wait until the pain has worsened, the medication may not work as well, codeine sulf tab 30mg. If you have ongoing pain such as due to canceryour codeine may direct you to also take long-acting opioid medications.
Sulf that case, this medication might be used for sudden breakthrough pain only as needed. Other pain 30mg such as acetaminophenibuprofen may also be prescribed. Ask your codeine or tab about using codeine safely with other drugs.
Acetaminophen & Codeine Phosphate Tablets, USP CIII 300/30 mg
This medication may cause withdrawal reactions, especially if it tab been used sulf for a long time or in high doses. In such 30mg, withdrawal symptoms such as codeine, watering eyescodeine sulf tab 30mg, runny nosenausea, sweatingmuscle aches may occur if you suddenly stop using this medication.
To prevent withdrawal reactions, your doctor may reduce your dose gradually. Ask your doctor or pharmacist for more details, and report any withdrawal reactions right away.
When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.
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