Clonazepam tablets usp 0.5mg - Clonazepam Oral : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD
Uses Uses Clonazepam clonazepam used to prevent and usp seizures. This medication is known as an anticonvulsant or antiepileptic drug. It is also used to 0.5mg panic attacks.
Clonazepam works by calming your brain and nerves. It belongs to a class of drugs called benzodiazepines. How to use Clonazepam Read the Medication Guide provided by your pharmacist before you start taking clonazepam and each tablet you get a refill, clonazepam tablets usp 0.5mg.
If you have any questions, ask your doctor or pharmacist. The possibility that a woman of childbearing potential may be pregnant at the time of institution of therapy should be considered. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential 0.5mg to the fetus.
Patients should usp be advised that if they become pregnant during therapy or intend to become pregnant, they should communicate with their physician about the desirability of discontinuing the drug.
When used in patients in whom several different types of seizure disorders clonazepam, clonazepam may increase the incidence or precipitate the onset of generalized tonic-clonic seizures grand mal.
This may require the addition of appropriate anticonvulsants or an increase in their dosages. The concomitant use of valproic acid and clonazepam may produce absence status. Periodic blood counts and liver function tests are advisable during long-term therapy with clonazepam.
The abrupt withdrawal of clonazepam, particularly in those patients on long-term, high-dose therapy, may precipitate status epilepticus. Therefore, when discontinuing clonazepam, gradual withdrawal is essential. While clonazepam is being gradually withdrawn, the simultaneous substitution of another anticonvulsant may be indicated.
What Is Isometheptene Mucate?
Metabolites of clonazepam are excreted by the kidneys; to avoid their excess accumulation, caution should be exercised in the administration of the drug to patients with impaired renal function. Clonazepam may produce an increase in salivation.
This should be considered before giving the drug to patients who have difficulty handling secretions. Because of this and the possibility of respiratory depression, clonazepam should be used with caution in patients with chronic respiratory diseases.
A clonazepam orally disintegrating tablets medication guide must be given to the patient clonazepam time clonazepam orally disintegrating tablets are dispensed, as required by law. Patients should be instructed to take clonazepam only as prescribed. Physicians are advised to discuss the following issues with patients clonazepam whom they prescribe clonazepam: To assure the safe and effective use of benzodiazepines, clonazepam tablets usp 0.5mg, patients should be informed that, clonazepam tablets usp 0.5mg, since benzodiazepines may produce psychological and physical dependence, it usp advisable that usp consult with their physician before either 0.5mg the dose or abruptly discontinuing this tablet. Because benzodiazepines have the potential to impair judgment, thinking or motor skills, patients should be cautioned about operating hazardous tablet, including automobiles, until they are reasonably certain that clonazepam therapy does not 0.5mg them adversely.
Chemically, clonazepam is 5- o-Chlorophenyl -1,3-dihydronitro-2 H-1,4-benzodiazepinone.
It is a light yellow crystalline powder. It has the following structural formula: Convulsions produced in rodents by pentylenetetrazol or, to a lesser extent, electrical stimulation are antagonized, as are convulsions produced by photic stimulation in susceptible baboons, clonazepam tablets usp 0.5mg.
Usp taming effect in aggressive primates, muscle weakness usp hypnosis are also produced. In tablets, clonazepam is capable of suppressing the spike and wave discharge in tablet seizures petit mal and decreasing the frequency, amplitude, clonazepam tablets usp 0.5mg, duration and spread of discharge in minor motor seizures, clonazepam tablets usp 0.5mg.
Pharmacokinetics Clonazepam clonazepam rapidly and completely absorbed after oral administration. Maximum plasma concentrations of clonazepam are reached within 1 to 4 hours after oral administration. Biotransformation occurs mainly by reduction of the 7-nitro group to the 4-amino derivative.
This derivative can be acetylated, hydroxylated, and glucuronidated. The elimination half-life of accutane price cvs is typically 30 to 40 hours. Clonazepam pharmacokinetics are dose-independent throughout the dosing range. There is no evidence that clonazepam induces its clonazepam metabolism or that of 0.5mg drugs in humans.
Pharmacokinetics in 0.5mg Subpopulations and in Disease States Controlled studies examining the influence of gender and age on clonazepam pharmacokinetics have not been conducted, nor have the effects of renal or liver disease on clonazepam pharmacokinetics been studied.
DESCRIPTION
Because clonazepam undergoes hepatic metabolism, it is possible that liver disease will impair clonazepam elimination. Thus, caution should be exercised when administering clonazepam to these patients.
Clinical Trials Panic Disorder: The effectiveness of clonazepam in the treatment of panic disorder was demonstrated in two double-blind, placebo-controlled studies of adult outpatients who had a primary diagnosis of panic disorder DSM-lllR with or without agoraphobia. Study 1 was a 9-week, fixed-dose study involving clonazepam doses of 0, clonazepam tablets usp 0.5mg.
This study was conducted in usp phases: The clonazepam between the 1 mg dose group and placebo in reduction from baseline in the number of full panic attacks was approximately 1 panic attack per week. Study 2 was a 6-week, 0.5mg tablet involving clonazepam in a dose range of 0, clonazepam tablets usp 0.5mg.
This study was conducted in three phases: The mean clonazepam dose during the optimal dosing period was 2. The difference between clonazepam and placebo in reduction from baseline in the number of full panic attacks was approximately 1 panic attack per week.
Subgroup analyses did not indicate that there were any differences in treatment outcomes as a function of race or gender. It is important to note that anticonvulsant drugs should not be discontinued in patients in whom the drug is administered to prevent seizures because of the strong possibility of precipitating status epilepticus with attendant hypoxia and threat to life. In individual cases where the severity and frequency of the seizure disorder are such that the removal 0.5mg medication does not clonazepam a serious threat to the patient, discontinuation of the drug may be considered prior to and during pregnancy; however, it cannot be said with any confidence that even mild seizures do not pose some hazards to the developing embryo or fetus.
General Concerns About Benzodiazepines: An increased risk of congenital malformations associated with the use of benzodiazepine drugs has been suggested in several studies. There may also be non-teratogenic risks associated with the use of benzodiazepines during pregnancy. There have been reports of neonatal flaccidity, respiratory and feeding difficulties, and hypothermia in children born to mothers who have been receiving benzodiazepines late in pregnancy.
In addition, children born to mothers receiving benzodiazepines late in pregnancy may be at some risk of experiencing withdrawal symptoms during the postnatal period. In general, the use of Clonazepam in women of childbearing potential, and more specifically farmaco zoloft 50mg known pregnancy, clonazepam tablets usp 0.5mg, should be considered only when the clinical situation warrants the risk to the fetus.
The specific considerations addressed above regarding the use of anticonvulsants for epilepsy in women of childbearing potential should be weighed in treating or counseling these women. Because of experience with other members of the benzodiazepine class, Clonazepam is assumed to usp capable of causing an increased risk of congenital abnormalities when administered to a pregnant woman during the first trimester.
Because use of these drugs is rarely a matter of urgency in the treatment of panic disorder, their use during the first trimester should almost always be avoided. The possibility that a woman of childbearing potential may be pregnant at the time of tablet of therapy should be considered.
If this drug clonazepam used during pregnancy, or if the patient becomes pregnant while 0.5mg this drug, the patient should usp apprised of the potential hazard to the fetus. Patients should also be advised that if they become pregnant usp therapy or intend to order ambien mastercard pregnant, they should communicate with their physician about the desirability of discontinuing the drug.
When used in patients in whom tablet different types of seizure disorders coexist, Clonazepam may increase the incidence or precipitate the onset of generalized tonic-clonic seizures grand mal. This may require the addition of appropriate anticonvulsants or an 0.5mg in their dosages, clonazepam tablets usp 0.5mg.
The concomitant use of valproic acid and Clonazepam may produce absence status. Periodic blood tablets and liver function tests are advisable during long-term therapy with Clonazepam.
Clonazepam of Abrupt Withdrawal: The abrupt withdrawal of Clonazepam, particularly in those patients on long-term, clonazepam tablets usp 0.5mg, high-dose therapy, may precipitate status epilepticus.
Clonazepam
Therefore, when discontinuing Clonazepam, gradual withdrawal is essential. While Clonazepam is being gradually withdrawn, clonazepam tablets usp 0.5mg, the simultaneous substitution of another anticonvulsant may be indicated.
Caution in Renally Impaired Patients: