Clarithromycin 1000mg - Clarithromycin: Uses, Dosage & Side Effects - 45.64.132.41
Follow the directions on your prescription label carefully, and ask your 1000mg or pharmacist to explain any part you do not understand. Take clarithromycin exactly clarithromycin directed, clarithromycin 1000mg. Do not take more or less of it or take it more often than prescribed by your doctor, clarithromycin 1000mg.
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Shake the suspension well before each use to mix the medication evenly. Clarithromycin the long-acting tablets clarithromycin do not split, chew, clarithromycin 1000mg, or crush them. You should begin to feel better during the first few days of treatment with clarithromycin. If your symptoms do not clarithromycin or get worse, 1000mg your doctor, clarithromycin 1000mg. If you have reduced liver function, discuss with your doctor how 1000mg medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special 1000mg is needed.
This medication should not be used by people with severe liver problems. If you develop symptoms of liver problems e. This 600mg zithromax can worsen or cause symptoms of myasthenia gravis.
If your symptoms worsen or you develop new symptoms such as double vision, drooping eyelids, muscle weakness, or difficulty chewing or swallowing, contact your doctor.
Clarithromycin is usually given for 7 to 14 days, clarithromycin 1000mg. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk clarithromycin infection that is resistant to medication. Clarithromycin will not treat a viral infection such as 1000mg flu or a common cold.
Clarithromycin Dosage
Store this medicine in the original container at room temperature, away from moisture, heat, and light. Do 1000mg keep the clarithromycin liquid in a refrigerator. Throw away any liquid that has not been used within 14 days.
If your infection is treated with a combination of drugs, use all medications as directed by your doctor, clarithromycin 1000mg. Read the instructions provided with each medication. Clarithromycin is principally excreted by the liver. Therefore, caution should be exercised in administering this antibiotic to patients with impaired hepatic function. Caution should also be exercised when administering clarithromycin to patients with moderate to severe renal impairment.
Cases of fatal hepatic failure see section 4. Some patients may have had pre-existing hepatic disease or may have been taking other hepatotoxic medicinal products.
Patients should be advised to stop treatment and contact 1000mg doctor if signs and symptoms of hepatic disease develop, such as anorexia, jaundice, dark urine, pruritus, or tender abdomen.
Pseudomembranous colitis has been reported with nearly all antibacterial agents, including macrolides, and may range in severity from mild to life-threatening, clarithromycin 1000mg. Clostridium difficile- associated diarrhoea CDAD has been reported with escitalopram 10mg y el alcohol of nearly all antibacterial agents including clarithromycin, and may range in severity from mild clarithromycin to fatal colitis.
Treatment with antibacterial agents alters the normal flora of the colon, which may lead to overgrowth of C. CDAD must be considered in all patients who present with diarrhoea following antibiotic use. Careful medical history is necessary since CDAD has been reported to occur clarithromycin two months after the administration of antibacterial agents.
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Clarithromycin
Therefore, discontinuation of clarithromycin therapy should be 1000mg regardless of the indication. Microbial testing should be performed and adequate treatment initiated. Drugs inhibiting peristalsis should be avoided. There have been post-marketing reports of colchicine toxicity with concomitant use of clarithromycin and 1000mg, especially in the elderly, some of which occurred in patients with renal insufficiency.
Deaths have been reported in some such patients see section 4. Concomitant administration of clarithromycin and colchicine is contraindicated see section 4. Caution is advised regarding concomitant administration of clarithromycin and triazolobenzodiazepines, clarithromycin 1000mg, such as triazolam, and intravenous or oromucosal midazolam see section 4.
Cardiovascular Events Prolonged cardiac repolarisation and QT interval, clarithromycin 1000mg, imparting a risk of developing cardiac arrhythmia and torsades 1000mg pointes, have been seen in treatment with macrolides including clarithromycin see section 4.
Clarithromycin clarithromycin not be given to patients with hypokalaemia see section 4. Epidemiological studies investigating the risk of adverse cardiovascular outcomes with macrolides have shown variable results. Clarithromycin observational studies have identified a rare short-term risk 1000mg arrhythmia, clarithromycin 1000mg, clarithromycin 1000mg, myocardial infraction and clarithromycin mortality clarithromycin with macrolides including clarithromycin.
Consideration of these findings should clarithromycin balanced with treatment benefits when prescribing clarithromycin. In view of the emerging resistance of Streptococcus pneumoniae to macrolides, it is important that sensitivity testing be performed when prescribing clarithromycin for community-acquired pneumonia.
In hospital-acquired pneumonia, 1000mg should be used in combination with additional appropriate antibiotics.
Skin and soft tissue infections of mild to moderate severity: These infections are most often caused by Staphylococcus aureus and Streptococcus pyogenes, both of which may be resistant to macrolides. Therefore, it is important that 1000mg testing be performed, clarithromycin 1000mg. In cases where beta—lactam antibiotics cannot clarithromycin used e, clarithromycin 1000mg.
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Currently, macrolides are only considered to play a role in some skin and soft tissue infections, such as those caused by Corynebacterium minutissimum erythrasmaacne vulgaris, and erysipelas and in situations where penicillin treatment cannot be used.
Due clarithromycin the high concentration in phagocytes, clarithromycin is actively transported to the site of infection. During active phagocytosis, large concentrations of clarithromycin are released; its concentration in the tissues can be over clarithromycin times higher than in plasma, clarithromycin 1000mg.
Highest concentrations are found in liver, lung tissue, and stool. Metabolism[ edit ] Clarithromycin has a fairly rapid first-pass metabolism in the liver. 1000mg adverse reactions have 1000mg reported in patients taking clarithromycin concomitantly with CYP3A4 substrates.
These include colchicine toxicity with colchicine; rhabdomyolysis with simvastatin, lovastatin, and atorvastatin; hypoglycemia with disopyramide; hypotension and acute kidney injury with calcium channel blockers metabolized by CYP3A4 e. Most reports of acute kidney injury with calcium 1000mg blockers clarithromycin by CYP3A4 involved elderly patients 65 years of age 1000mg older. Use clarithromycin with caution when administered 1000mg with medications that induce the cytochrome CYP3A4 enzyme, clarithromycin 1000mg.
The use of clarithromycin with simvastatin, clarithromycin 1000mg, lovastatin, ergotamine, clarithromycin 1000mg, or dihydroergotamine is contraindicated [see Contraindications 1000mg. Life-threatening and fatal drug interactions have been reported in patients treated with clarithromycin and colchicine. Clarithromycin is clarithromycin strong CYP3A4 inhibitor clarithromycin this interaction may occur while using both drugs at their recommended doses, clarithromycin 1000mg.
If co-administration of clarithromycin and colchicine is necessary in patients with normal renal and hepatic function, reduce the clarithromycin of colchicine.
