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Prednisone Oral : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD
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This medication may cause vaccines not medicine mebeverine 135mg prednisone as well. Avoid contact with people who have recently received kit vaccines such as flu vaccine inhaled through the nose. This medicine may cause stomach bleeding. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding, prednisone 5 mg kit. Consult your doctor or pharmacist for more information.
This medication may slow down a child's growth if used for a long time. Consult the doctor or pharmacist for more details, prednisone 5 mg kit. See the prednisone regularly so your child's height kit growth can be checked.
During pregnancythis medication should be used only when clearly needed. It may rarely harm an unborn baby. Discuss the risks and benefits with your doctor.
Infants born to mothers who have been using this medication for an extended period of time may have hormone problems. This medication passes into breast milk but is unlikely to harm a nursing infant.

Tendon rupture can occur during or after treatment with quinolones. Drugs which inhibit CYP 3A4 e. Glucocorticoids are moderate inducers of CYP 3A4. Co-administration with other drugs that are metabolized by CYP 3A4 e. In addition, ketoconazole alone can inhibit adrenal corticosteroid synthesis and may cause adrenal insufficiency during corticosteroid withdrawal. Nonsteroidal Anti-Inflammatory Agents NSAIDS Concomitant use of aspirin or other nonsteroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects.
Aspirin should be used cautiously in conjunction with corticosteroids in hypoprothrombinemia. The clearance of salicylates may be increased with concurrent use of corticosteroids; this could lead to decreased salicylate serum levels or increase the risk of salicylate toxicity when corticosteroid is withdrawn. Phenytoin In post-marketing experience, there have been reports of both increases and decreases in phenytoin levels with dexamethasone co-administration, prednisone 5 mg kit, leading to kit in seizure control.
Phenytoin has been demonstrated to increase the hepatic metabolism of corticosteroids, resulting in a decreased therapeutic effect of the corticosteroid. Quetiapine Increased doses of quetiapine may be required to maintain prednisone of symptoms of schizophrenia in patients receiving a glucocorticoid, a hepatic enzyme inducer.
Skin Tests Corticosteroids may suppress reactions to skin tests. Thalidomide Co-administration with thalidomide should be employed cautiously, as toxic epidermal necrolysis has been reported with concomitant use.
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Vaccines Patients on corticosteroid therapy may exhibit a diminished response to toxoids and live or inactivated vaccines due to inhibition of antibody response. Corticosteroids may also potentiate the replication of some organisms contained in live attenuated vaccines. Carcinogenesis, prednisone 5 mg kit, Mutagenesis, Impairment of Fertility No adequate studies have been conducted in animals to determine whether corticosteroids have a prednisone for carcinogenesis or mutagenesis.
Steroids may increase or decrease motility and number of spermatozoa in some patients. Pregnancy Teratogenic Effects Pregnancy Category C Corticosteroids have been shown to be teratogenic in many species when given in doses equivalent to the human dose. Animal studies in which corticosteroids have been kit to pregnant mice, rats, and rabbits have yielded an increased prednisone kit cleft palate in the offspring. There are no adequate and well-controlled studies in pregnant women, prednisone 5 mg kit.
Corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Infants born to mothers who have received substantial doses of corticosteroids during pregnancy should be carefully observed for signs of hypoadrenalism.

Nursing Mothers Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects. Because of the potential for serious adverse reactions in nursing infants from corticosteroids, a decision should be made whether to kit nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Pediatric Use The efficacy and safety of corticosteroids in the pediatric population are based on the well-established course of effect of corticosteroids, which is similar in pediatric and adult populations. Other indications for pediatric use of corticosteroids, e. Like adults, pediatric patients should be carefully observed with frequent measurements of blood pressure, weight, height, intraocular pressure, and clinical evaluation for the presence of infection, psychosocial disturbances, thromboembolism, peptic ulcers, cataracts, and osteoporosis.
Pediatric patients who are treated with corticosteroids by any route, including systemically administered corticosteroids, may experience a decrease in their growth velocity. This negative impact of corticosteroids on growth has been observed at low systemic doses and in the absence of laboratory evidence of hypothalamic-pituitary-adrenal HPA axis suppression i.
Growth velocity may therefore be a more sensitive indicator of systemic corticosteroid exposure in pediatric patients than some commonly used tests of HPA axis function.
The linear growth of pediatric patients treated with corticosteroids should be monitored, and the potential growth effects of prolonged treatment should be weighed against clinical benefits obtained and the availability of treatment alternatives.
In order to minimize the potential growth effects of corticosteroids, pediatric patients should be titrated to the lowest effective dose. Kit Use Clinical studies did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical claritin breastfeeding supply has not identified differences in responses between the elderly and younger patients.
In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. In particular, the increased risk of diabetes mellitus, fluid retention and hypertension in elderly patients treated with corticosteroids should be considered. Adverse Reactions listed alphabetically, under each subsection The following adverse reactions have been reported with Prednisone or other corticosteroids: Allergic Reactions anaphylactoid or hypersensitivity reactions, anaphylaxis, angioedema.
Cardiovascular System bradycardia, cardiac arrest, cardiac arrhythmias, cardiac enlargement, prednisone 5 mg kit, circulatory collapse, congestive heart failure, ECG changes caused by potassium deficiency, edema, fat embolism, hypertension or aggravation of hypertension, hypertrophic cardiomyopathy in premature infants, myocardial rupture following recent myocardial infarction see WARNINGS: Cardio-Renalnecrotizing angiitis, pulmonary edema, syncope, tachycardia, thromboembolism, thrombophlebitis, vasculitis.
General Precautionslupus erythematosus-like lesions, perineal irritation, purpura, rash, prednisones, subcutaneous fat atrophy, suppression of reactions to skin tests, striae, telangiectasis, thin fragile skin, thinning scalp hair, urticaria. Endocrine Adrenal insufficiency-greatest potential caused by high potency glucocorticoids with long duration of action associated symptoms include; arthralgias, buffalo hump, dizziness, life-threatening hypotension, nausea, severe tiredness or weaknessamenorrhea, postmenopausal bleeding or other menstrual irregularities, decreased carbohydrate and glucose tolerance, development of cushingoid state, prednisone 5 mg kit, diabetes mellitus new onset or manifestations of latentglycosuria, hyperglycemia, hypertrichosis, hyperthyroidism see WARNINGS: Endocrineprednisone 5 mg kit, hypothyroidism, increased requirements for insulin or oral hypoglycemic agents in diabetics, lipids abnormal, moon face, negative nitrogen balance caused by protein catabolism, secondary adrenocortical and pituitary unresponsiveness particularly in times of stress, as in trauma, surgery or illness see WARNINGS: Endocrinesuppression of growth in pediatric patients.
Fluid and Electrolyte Disturbances congestive heart failure in susceptible patients, fluid retention, hypokalemia, hypokalemic alkalosis, metabolic alkalosis, hypotension or shock-like reaction, potassium loss, prednisone retention with resulting edema, prednisone 5 mg kit. Gastrointestinal abdominal distention, abdominal pain, anorexia which may result in weight loss, constipation, diarrhea, kit in serum liver enzyme levels usually reversible upon discontinuationgastric irritation, hepatomegaly, increased appetite and weight gain, nausea, oropharyngeal candidiasis, pancreatitis, peptic ulcer with possible perforation and hemorrhage, perforation of the small and large intestine particularly in patients with inflammatory bowel diseaseulcerative esophagitis, vomiting.
Hematologic anemia, neutropenia including febrile neutropenia. Metabolic negative nitrogen balance due to protein prednisone. Musculoskeletalpathologic fracture of long bones, steroid myopathy, tendon rupture particularly of the Achilles tendonvertebral compression fractures. Ophthalmicoptic nerve damage, papilledema.

Infectionhiccups, immunosuppresion, increased or decreased motility and number of spermatozoa, malaise, insomnia, moon face, pyrexia. Prednisone Dosage and Administration Gastric irritation may be reduced if taken before, during, or immediately after meals or with food or milk. The maximal activity of the adrenal cortex is between 2 am and 8 am, and it is minimal between 4 pm and midnight. Exogenous corticosteroids suppress adrenocorticoid activity the least when given at the time of maximal activity am for single dose administration.
Therefore, it is recommended that Prednisone kit administered in the morning prior to 9 am and when large doses are given, administration of antacids between meals to help prevent peptic ulcers. Multiple dose therapy should be evenly distributed in evenly spaced intervals throughout the day. Dietary salt restriction may be advisable in patients. Do not stop taking this medicine without first talking to your doctor. Avoid abrupt withdraw of therapy.
The initial dosage of Prednisone may vary from 5 mg to 60 mg per day, depending on the prednisone disease entity being treated. In situations of less severity lower doses will generally suffice, while in selected patients higher initial doses may be required. The initial dosage should be maintained or adjusted until long term effects dexamethasone treatment satisfactory response is noted.
If after a reasonable period of time there is a lack of satisfactory clinical response, Prednisone should be discontinued and the patient transferred to other kit prednisone. After a favorable response is noted, the proper maintenance dosage should be determined by decreasing the initial drug dosage in small increments at appropriate time intervals until the lowest dosage which will maintain an adequate clinical response is reached.
It should be kept in mind that constant monitoring is needed in regard to drug dosage. If after long-term therapy the drug is to be stopped, prednisone 5 mg kit, it recommended that it be withdrawn gradually rather than abruptly. Multiple Sclerosis In the treatment of acute exacerbations of multiple sclerosis daily doses of mg of prednisolone for a week followed by 80 mg every other day for 1 month have been shown to be effective.
Dosage range is the same for Prednisone and prednisolone. Alternate Day Therapy Alternate day therapy is a corticosteroid dosing regimen in which twice the usual daily dose of corticoid is administered every other morning.
The purpose of this mode of therapy is to provide the patient requiring long-term pharmacologic dose treatment with the kit effects of corticoids while minimizing certain undesirable effects, including pituitary-adrenal suppression, the cushingoid state, corticoid withdrawal symptoms, and growth suppression in children, prednisone 5 mg kit.
The rationale for this treatment schedule is based on two major premises: A brief review of the HPA physiology may be helpful in understanding this prednisone. Acting primarily through the hypothalamus a fall in free cortisol stimulates the pituitary gland to produce increasing amounts of corticotropin ACTH while a rise in free cortisol inhibits ACTH secretion, prednisone 5 mg kit.
Normally the HPA system is characterized by diurnal circadian rhythm.

Serum prednisones of ACTH rise from a low point about 10 pm to a peak level about 6 am. Increasing levels of ACTH stimulate adrenocortical prednisone resulting in a rise in plasma cortisol with maximal levels occurring between 2 am and 8 am. This rise in cortisol dampens ACTH production and in turn adrenocortical activity, prednisone 5 mg kit. There is a gradual fall in plasma corticoids during the day prilosec otc oral drug lowest levels occurring about midnight.
The same clinical findings of hyperadrenocorticism may be noted during long-term pharmacologic dose corticoid therapy administered in conventional daily divided doses. It kit appear, then, that a disturbance in the diurnal cycle with maintenance of elevated corticoid values during the night kit play a significant role in the development of undesirable corticoid effects.

Escape from these constantly prednisone plasma levels for even short periods of time may kit instrumental in protecting against undesirable pharmacologic effects. During conventional pharmacologic dose corticosteroid kit, ACTH production is inhibited with subsequent suppression of cortisol production by the adrenal cortex, prednisone 5 mg kit. Recovery time for normal HPA activity is variable depending upon the dose and duration of treatment. During this time the patient is vulnerable to any stressful situation, prednisone 5 mg kit.
Although it has been shown that there is considerably less adrenal suppression following a single morning dose of prednisolone 10 mg as opposed to a quarter of that dose administered every 6 hours, there is evidence that some suppressive effect on adrenal activity may be carried over into the following day when pharmacologic doses are used.
Further, it has been shown that a single dose of certain corticosteroids will produce adrenocortical suppression for two or more days. The following should be kept in mind when considering kit day therapy: Basic principles and indications for corticosteroid therapy should apply, prednisone 5 mg kit.
The benefits of alternate day therapy should not encourage the indiscriminate use of steroids. Alternate day therapy is a therapeutic prednisone primarily designed for patients in whom long-term pharmacologic corticoid therapy is anticipated. In less severe disease processes in which corticoid therapy is indicated, it may be possible to prednisone treatment with alternate day therapy. More severe disease states usually will require daily divided prednisone dose therapy for initial control of the disease process.
The initial suppressive dose level should be continued until satisfactory clinical response is obtained, prednisone 5 mg kit, usually four to ten days in the case of many allergic and collagen diseases. It is important to keep the period of initial suppressive dose as brief as possible particularly when subsequent use of alternate day therapy is intended. Once control has been established, prednisone 5 mg kit, two courses kit available: Theoretically, prednisone 5 mg kit, course a may be preferable.
Because of the advantages of alternate day therapy, it may be desirable to try prednisones on this form kit therapy who have been on daily corticoids for long periods of time e, prednisone 5 mg kit. Since these patients may already have a suppressed HPA axis, establishing them on alternate day therapy may be difficult and not always successful, prednisone 5 mg kit. However, it is recommended that regular attempts be made to change them over.
It may be helpful to triple or even quadruple the daily maintenance dose and administer this every other day rather than just doubling the daily dose if difficulty is encountered.
Once the patient is again controlled, an attempt should be made to reduce this prednisone to a minimum. As indicated prednisone, certain corticosteroids, because of their prolonged suppressive prednisone on adrenal activity, are not kit for alternate day therapy e.
Exogenous corticosteroids suppress adrenocortical activity the least, when given at the time of maximal activity am. In using alternate day therapy it is important, as in all therapeutic situations to individualize and tailor the therapy to each patient. Complete control of symptoms will not be possible in all patients. An explanation of the benefits of alternate day therapy will help the patient to understand and tolerate the possible flare-up in symptoms which may occur in the latter part of the off-steroid day.
Other symptomatic therapy may be added or increased at this time if needed. In the event of an acute flare-up of the disease process, prednisone 5 mg kit, it may be necessary to return to a full suppressive daily divided corticoid dose for control.
Once control is again established alternate day therapy may be re-instituted. Although many of the undesirable features of corticosteroid therapy can be minimized by alternate day therapy, as in any therapeutic situation, the physician must carefully weigh the benefit-risk ratio for each patient in whom corticoid therapy is being considered.
Bottle of Tablets NDC chlorpromazine 50 mg alcohol Kit of 1, prednisone 5 mg kit, Tablets 2, prednisone 5 mg kit. Bottle of mL NDC kit Bottle of 30 mL with calibrated dropper graduations of 0. Discard opened bottle after 90 days.