Your medicine, exercise plan , or diet may need to be adjusted. This drug may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. These patients experience severe pain in the involved joints, and can require joint replacements. The reason behind such destruction is not clear.

What is the dosage of prednisone vs. Prednisone The initial dosage of prednisone varies depending on the condition being treated and the age of the patient.

It's recommended that you take this medication with food. The starting dose may be from 5 mg to 60 mg per day, and often is adjusted based on the response of the disease or condition being treated. Corticosteroids typically do not produce immediate effects and must be used for several days before maximal effects are seen. It may take much longer before conditions respond to treatment.

When prednisone is discontinued after a period of prolonged therapy, the dose of prednisone must be tapered lowered gradually to allow the adrenal glands time to recover. Dexamethasone Dosage requirements of corticosteroids vary greatly among individuals and the diseases being treated. In general, the lowest possible effective dose is used. Child dosage ages 0—17 years Initial dosage: Dosage depends on the condition being treated. Senior dosage ages 65 years and older The kidneys and liver of older adults may not work as well as they used to.

This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects. Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body.

Special dosage considerations When stopping treatment, your dosage should be decreased slowly over time. This helps to prevent withdrawal side effects. As prolonged use may cause adrenal insufficiency and make patients dependent on corticosteroids, they should advise any medical attendants that they are taking corticosteroids and they should seek medical advice at once should they develop an acute illness including fever or other signs of infection. Following prolonged therapy, withdrawal of corticosteroids may result in symptoms of the corticosteroid withdrawal syndrome including, myalgia, arthralgia, and malaise.

Persons who are on corticosteroids should be warned to avoid exposure to chickenpox or measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.

Drug Interactions Aminoglutethimide may diminish adrenal suppression by corticosteroids. Amphotericin B injection and potassium-depleting agents When corticosteroids are administered concomitantly with potassium-depleting agents e. In addition, there have been cases reported in which concomitant use of amphotericin B and hydrocortisone was followed by cardiac enlargement and congestive heart failure.

Antibiotics Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance see Drug Interactions: Hepatic Enzyme Inducers, Inhibitors and Substrates.

Anticholinesterases Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. If possible, anticholinesterase agents should be withdrawn at least 24 hours before initiating corticosteroid therapy. Anticoagulants, Oral Co-administration of corticosteroids and warfarin usually results in inhibition of response to warfarin, although there have been some conflicting reports.

Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. Antidiabetics Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. Antitubercular Drugs Serum concentrations of isoniazid may be decreased. Cholestyramine Cholestyramine may increase the clearance of corticosteroids.

Cyclosporine Increased activity of both cyclosporine and corticosteroids may occur when the two are used concurrently. Convulsions have been reported with this concurrent use. Thus, results of the DST should be interpreted with caution in these patients. Metabolic disorders At high doses, sufficient calcium intake and sodium restriction, as well as serum potassium levels should be monitored.

Depending on the length and dosage of the treatment, a negative influence on calcium metabolism can be expected, so that an osteoporosis prophylaxis is recommended.

This applies, above all, to co-existing risk factors like familial disposition, increased age, after menopause, insufficient protein and calcium intake, heavy smoking, excessive alcohol intake, as well as insufficient exercise. Prevention consists of sufficient calcium and vitamin D intake and physical activity. Additional medical treatment should be considered in the event of pre-existing osteoporosis.

Corticosteroids should be used cautiously in patients with migraine, as corticosteroids may cause fluid retention. Psychological changes Psychological changes are manifested in various forms, the most common being euphoria. Depression, psychotic reactions and suicidal tendencies may also appear.

These illnesses can be serious. Usually they start within a few days or weeks of starting the medicine. They are more likely to happen at high doses. Most of these problems go away if the dose is lowered or the medicine is stopped. However, if problems do happen, they might need treatment. In a few cases, mental health problems have happened when doses are being lowered or stopped.

Cerebral oedema or increased intracranial pressure Corticosteroids should not be used in conjunction with a head injury since they will probably not be of benefit or may even do harm. Discontinuation of treatment Glucocorticoid doses should be gradually reduced.

The following risks should be considered upon interruption or discontinuation of long-term glucocorticoid administration: If these people have contact with people infected with measles or chickenpox while undergoing treatment with dexamethasone, a preventative treatment should be introduced if necessary.

Other Pheochromocytoma crisis, which can be fatal, has been reported after administration of systemic corticosteroids. Paediatric population Corticosteroids cause a dose-dependent inhibition of growth in infancy, childhood, and adolescence since corticosteroids may give rise to early closing of the epiphyses, which may be irreversible. Therefore, during long-term treatment with dexamethasone, the indication should be very strongly presented in children and their growth rate should be checked regularly.

Elderly The adverse effects of systemic corticosteroids can have serious consequences especially in old age, mainly osteoporosis, hypertension, hypokalemia, diabetes, susceptibility to infection and skin atrophy. Close clinical monitoring is required to prevent life-threatening reactions. Influence of diagnostic tests Glucocorticoids can suppress skin reaction to allergy testing.

They can also affect the nitroblue tetrazolium test for bacterial infections and cause false-negative results. Note on doping The use of doping tests when taking dexamethasone can lead to positive results. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicinal product.

Acetylsalicylic acid should be used carefully in combination with corticosteroids in hypoprothrombinaemia. The renal clearance of salicylates is increased by corticosteroids. Therefore, the dosage of salicylates may be reduced once the steroids are discontinued. Steroid withdrawal may result in salicylate intoxication due to the increase of salicylate concentration in the serum. If you suffer from schizophrenia or epilepsy your symptoms may worsen.

You may experience more frequent and severe infections without noticing the symptoms as well as opportunistic infections caused by a usually harmless microorganism in case of an impaired immune system or the recurrence of dormant tuberculosis. You may develop sterile abscesses enclosed collections of pus, likely to turn into hard solid lumps as they scar. There may be an abnormal increase in the number of white blood cells. Hormonal endocrine disorders Menstrual irregularities, lack of menstruation, abnormal hair growth, development of Cushingoid state symptoms of which include central obesity with thin arms, thinning of the skin with easy bruising, muscle wasting and weakness, high blood pressure, uncontrolled blood sugar, osteoporosis.

Children and adolescents may have suppressed growth. Your response to stress caused by trauma, surgery or illness may be reduced. You may also experience decreased carbohydrate tolerance, onset of latent diabetes mellitus, increased need for insulin or other medicines if you are diabetic.

You may notice that you gain weight or have an increased appetite. Your body may also have difficulty in handling nitrogen, calcium, sodium or potassium appropriately. You may feel increased pressure in your head with impaired vision, vertigo, headache or in preterm infants cerebral palsy malformation of the brain may occur. You may develop cataracts or feel increased pressure in the eye or notice abnormal bulging out of the eyeballs or thinning of the cornea or the white, outer coat of the eyeball.

Your vision may become blurred due to congestion of the optic disc or glaucoma with possible damage to the optic nerves.

DEXAMETHASONE 6.6 MG/ML SOLUTION FOR INJECTION

Prescribing physicians should carefully evaluate which dose of dexamethasone to use, taking into account the condition and disease status of the patient. The following risks should be considered upon interruption or discontinuation of long-term glucocorticoid administration: Having strange and frightening thoughts, changing how you act or having feelings of being alone. Various Prevention and treatment of postoperative vomiting, pregnancy antiemetic treatment. This helps dexamethasone prevent withdrawal side effects. White or almost white, round tablets with bevelled edges and scored on one side Thickness: However, patients who have received corticosteroids locally parenteral or for a short period of time less than 2 weeksin smaller doses may be immunised. In case of high doses or of dexamethasone lasting over 10 days there is a risk of bleeding specific to corticosteroid therapies gastrointestinal mucosa, vascular fragility. The drug information contained herein is pregnancy to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, dexamethasone 6 mg pregnancy, or adverse effects. Wounds may take longer to heal, dexamethasone 6 mg pregnancy, skin tests may be affected and you may sweat more. Elderly The adverse effects of systemic corticosteroids can have serious consequences especially in old age, dexamethasone 6 mg pregnancy, mainly osteoporosis, hypertension, hypokalemia, diabetes, susceptibility to infection and skin atrophy.

What is the purpose of steroid shots during pregnancy?

Dexamethasone Pregnancy and Breastfeeding Warnings

Child dosage ages 0—17 years Initial dosage: There may be an abnormal pregnancy in the number of white blood cells. After prolonged therapy your body may have gotten used to the pregnancy of this dexamethasone and may have reduced the normal production of hormones like the one contained in this medicine, dexamethasone 6 mg pregnancy. Treatment is probably not indicated for pregnancies due to chronic poisoning unless the patient has a condition that would render him unusually susceptible to ill effects from corticosteroids. If you are treated for multiple myeloma with dexamethasone in combination with lenalidomide or thalidomide you will have an increased risk of thromboembolic events including: Our goal is to provide you with the most relevant and current information. Kaposi's sarcoma has been reported to occur in dexamethasone receiving corticosteroid therapy, dexamethasone 6 mg pregnancy, dexamethasone often for chronic conditions. Psychiatric disorders mental health problems Steroids including dexamethasone can cause serious mental health problems. Endocrine Drug-induced secondary adrenocortical insufficiency may be minimized by gradual reduction of dosage. The risk of hypokalemia high potassium levels in the blood increases when corticosteroids are combined with drugs that reduce potassium levels for example, amphotericin B, diureticsleading to serious side effects such as heart enlargement, heart arrhythmias and congestive heart failure. Susceptible patients may develop heart failure, or the heart tissue may rupture following a recent heart attack. Muscle and bone disorders You may suffer muscle weakness, loss of muscle mass, osteoporosis loss of bone density especially if you are postmenopausal, vertebral compression fractures collapsing of a bone in the spineaseptic necrosis of dexamethasone and humeral heads severe knee and hip joint problem, possibly requiring replacement jointsfracture dexamethasone long bones, tendon rupture, dexamethasone 6 mg pregnancy, postinjection flare following local injection e. In a few cases, mental health problems have occurred when doses are being lowered or stopped — see section 4 below. Your doctor has to make sure that the disease you have been treated for is unlikely to relapse. Don't store this medication in moist or damp areas, dexamethasone 6 mg pregnancy, such as bathrooms. In addition, treatment with dexamethasone should only be implemented under strong indications and, if necessary, additional specific treatment must be implemented for: In particular, the increased pregnancy of diabetes mellitus, fluid retention and hypertension in elderly patients treated with corticosteroids should be considered.

How many times ultrasound is safe during pregnancy? - Dr. Uzma Zeenath Taher

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